An article entitled "Genetic diagnosis in multiple pregnancies: Aminocentesis versus chorionic villus sampling" provided much information that I had not found previously. As indicated in the title, this article compares amniocentesis to chorionic villus sampling. Both of these procedures produce information for genetic defects.
According to Boris Furman and Zvi Appelman, chorionic villus sampling has a significant advantage over amniocentesis, because it offers rapid karyotyping and biochemical or DNA studies at an earlier stage of pregnancy. CVS is done in the first-trimester whereas amniocentesis is in the second-trimester.
The process of CVS is performed by inserting a 22 gauge needle, guided by ultrasound, into one sac and fluid is retrieved. One to two milliliters of an inert dye is injected and the needle is withdrawn. In the same fashion a second needle is inserted into the second gestational sac under ultrasound guidance and clear, dye-free fluid is retrieved. Amniocentesis is performed the same way but without using a dye.
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