Division Of Medical Genetics, Department Of Human Genet (2002). "About Chorionic Villus Sampling." Emory University School of Medicine. Retrieved March 1, 2008, from http://www.genetics.emory.edu

The process of chorionic villus sampling is described in full detail. The main purpose for this procedure is to determine any possible genetic defects. A small sample is taken from the mother’s uterus either transvaginally or transabdominally. Ultrasound is used as a guide to locate the placenta where the best sample may be taken. If performed transvaginally, the cervical and vaginal areas are cleaned with an antiseptic solution. A thin catheter is then inserted through the cervix into the uterus in order to extract the tissue sample. This process takes about two to three minutes with only mild discomfort. When CVS is performed transabdominally, a thin needle is inserted through the mother’s abdomen into the uterus. Pain such as menstrual-like cramping is common for both of these procedures. Exercise and heavy lifting is not suggested for two to three days after CVS along with avoiding sexual intercourse and use of tampons. Chorionic villus sampling is offered to: women who will be thirty five years of age or greater at delivery, individuals who already have children with chromosome problems, individuals who have chromosomal abnormalities themselves, couples who have a family history of genetic diseases, or an ultrasound indicating possible fetal abnormalities.